Pub. Date : 2014 Aug
PMID : 24793484
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Overexpression of apoA-I in mice reduced hepatic lipid levels, 27-hydroxycholesterol levels, and the mRNA levels of fatty acid synthase and acetyl-CoA carboxylase 1. | Hydroxycholesterols | apolipoprotein A-I | Mus musculus |
2 | These results suggest that expression of apoA-I or ABCA1 can reduce steatosis by decreasing lipid storage and modifying lipid transport in hepatocytes and may also inhibit fatty acid synthesis by decreasing 27-hydroxycholesterol levels. | Hydroxycholesterols | apolipoprotein A-I | Mus musculus |