Pub. Date : 2008
PMID : 24790369
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Subsequent molecular studies have shown that the mouse homolog is transiently expressed in fetal Sertoli and Leydig cells around the critical period for sex development, and that transient knockdown of Mamld1 results in significantly reduced testosterone production in murine Leydig tumor cells. | Testosterone | mastermind-like domain containing 1 | Mus musculus |
| 2 | These findings suggest that the MAMLD1 mutations cause hypospadias primarily because of compromised testosterone production around the critical period for sex development. | Testosterone | mastermind-like domain containing 1 | Mus musculus |