Pub. Date : 2014 Jun
PMID : 24771866
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A new mechanism for formation of 7-ketocholesterol was recently described involving cytochrome P-450 (CYP)7A1-catalyzed conversion of 7-dehydrocholesterol into 7-ketocholesterol with cholesterol-7,8-epoxide as a side product. | 7-ketocholesterol | cytochrome P450 family 7 subfamily A member 1 | Homo sapiens |
| 2 | A new mechanism for formation of 7-ketocholesterol was recently described involving cytochrome P-450 (CYP)7A1-catalyzed conversion of 7-dehydrocholesterol into 7-ketocholesterol with cholesterol-7,8-epoxide as a side product. | 7-ketocholesterol | cytochrome P450 family 7 subfamily A member 1 | Homo sapiens |
| 3 | Downregulation of CYP7A1 activity by treatment with chenodeoxycholic acid reduced the levels of 7-ketocholesterol in parallel with decreased levels of 7-dehydrocholesterol and cholesterol-7,8-epoxide. | 7-ketocholesterol | cytochrome P450 family 7 subfamily A member 1 | Homo sapiens |