Title : Damnacanthal is a potent inducer of apoptosis with anticancer activity by stimulating p53 and p21 genes in MCF-7 breast cancer cells.

Pub. Date : 2014 May

PMID : 24765160






2 Functional Relationships(s)
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1 Damnacanthal induced apoptosis, determined by Annexin V-fluorescein isothiocyanate/propidium iodide (PI) dual-labeling, acridine-orange/PI dyeing and caspase-7 expression. damnacanthal caspase 7 Homo sapiens
2 Overall, the present study provided significant evidence demonstrating that p53-mediated damnacanthal induced apoptosis through the activation of p21 and caspase-7. damnacanthal caspase 7 Homo sapiens