Pub. Date : 2014
PMID : 24762600
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin increased the expression of SIRT3 (1.5-fold) and SOD2 (2-fold) while down regulating NF-kappaB p65 (1.5-fold) and JNK1 (1.5-fold). | Metformin | superoxide dismutase 2 | Rattus norvegicus |
| 2 | Knockdown of SIRT3 (P < 0.05) reversed the metformin-induced decreases in NF-kappaB p65 and JNK1 and the metformin-induced increase in SOD2 (P < 0.05). | Metformin | superoxide dismutase 2 | Rattus norvegicus |