Title : CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

Pub. Date : 1989 Sep 1

PMID : 2475570






1 Functional Relationships(s)
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1 CD59 antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria. Phosphatidylinositols CD59 molecule (CD59 blood group) Homo sapiens