Pub. Date : 2014 Jun
PMID : 24746831
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway. | Quercetin | hepcidin antimicrobial peptide | Mus musculus |
| 2 | In contrast, co-treatment with iron and ethanol, especially exposure of iron alone, activated BMP6/SMAD4 pathway and up-regulated hepcidin expression, which was also normalized by quercetin in vivo. | Quercetin | hepcidin antimicrobial peptide | Mus musculus |
| 3 | Quercetin prevented ethanol-induced hepatic iron overload different from what carbonyl iron diet elicited in the mechanism, by regulating hepcidin expression via the BMP6/SMAD4 signaling pathway. | Quercetin | hepcidin antimicrobial peptide | Mus musculus |