Title : The in vitro estrogenic activities of triclosan and triclocarban.

Pub. Date : 2014 Sep

PMID : 24740835






2 Functional Relationships(s)
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1 The tested concentrations of TCS and TCC were both from 1 x 10(-9) to 1 x 10(-6) M. Results showed that TCS and TCC exerted estrogenic activities by inducing luciferase activities in an ER reporter gene assay, promoting the proliferation of the MCF-7 cells, up-regulating the expression of pS2 and down-regulating ERalpha expression at both the mRNA and protein levels in the MCF-7 cells. triclocarban estrogen receptor 1 Homo sapiens
2 The tested concentrations of TCS and TCC were both from 1 x 10(-9) to 1 x 10(-6) M. Results showed that TCS and TCC exerted estrogenic activities by inducing luciferase activities in an ER reporter gene assay, promoting the proliferation of the MCF-7 cells, up-regulating the expression of pS2 and down-regulating ERalpha expression at both the mRNA and protein levels in the MCF-7 cells. triclocarban estrogen receptor 1 Homo sapiens