Title : Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotype.

Pub. Date : 2014

PMID : 24733089






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Higher expression levels of MITF-dependent genes that are responsible for differentiation, e.g., TYR and MLANA, and stemness-related genes, e.g., ALDH1A1, were detected in melanospheres. Tyrosine melanocyte inducing transcription factor Homo sapiens