Title : Rhein exerts pro- and anti-inflammatory actions by targeting IKK╬▓ inhibition in LPS-activated macrophages.

Pub. Date : 2014 Jul

PMID : 24721152






1 Functional Relationships(s)
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1 But in the meantime, rhein enhances the activity of caspase-1 by inhibiting intracellular (in situ) IKKbeta, in turn increasing the IL-1beta and high-mobility-group box 1 release, which can be amplified by rhein s reductive effect on intracellular superoxide anion. Superoxides interleukin 1 beta Homo sapiens