Title : CD38 mediates the intracellular ATP levels and cell survival of C6 glioma cells.

Pub. Date : 2014 May 28

PMID : 24713601






5 Functional Relationships(s)
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1 CD38 mediates the intracellular ATP levels and cell survival of C6 glioma cells. Adenosine Triphosphate CD38 molecule Homo sapiens
2 In this study, we applied CD38 small interfering RNA (siRNA) to determine the effects of decreased CD38 on the intracellular ATP levels and survival of C6 glioma cells. Adenosine Triphosphate CD38 molecule Homo sapiens
3 Our study showed that both CD38 siRNA and 8-bromo-cADPR - a ryanodine receptor antagonist - can lead to a significant increase in the intracellular ATP levels of C6 glioma cells. Adenosine Triphosphate CD38 molecule Homo sapiens
4 In summary, our study has provided novel evidence suggesting that CD38 mediates both the intracellular ATP levels and the survival of C6 glioma cells, suggesting that CD38 may become a therapeutic target for gliomas. Adenosine Triphosphate CD38 molecule Homo sapiens
5 In summary, our study has provided novel evidence suggesting that CD38 mediates both the intracellular ATP levels and the survival of C6 glioma cells, suggesting that CD38 may become a therapeutic target for gliomas. Adenosine Triphosphate CD38 molecule Homo sapiens