Pub. Date : 2014 May 2
PMID : 24704449
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We found that (+)-nootkatone inhibited the TNF-alpha/IFN-gamma-induced expression of TARC/CCL17 and MDC/CCL22 mRNA in HaCaT cells. | nootkatone | C-C motif chemokine ligand 22 | Homo sapiens |
2 | We found that (+)-nootkatone inhibited the TNF-alpha/IFN-gamma-induced expression of TARC/CCL17 and MDC/CCL22 mRNA in HaCaT cells. | nootkatone | C-C motif chemokine ligand 22 | Homo sapiens |
3 | Taken together, these results suggest that (+)-nootkatone may suppress TNF-alpha/IFN-gamma-induced TARC/CCL17 and MDC/CCL22 expression in HaCaT cells by inhibiting of PKCzeta and p38 MAPK signaling pathways that lead to activation of NF-kappaB. | nootkatone | C-C motif chemokine ligand 22 | Homo sapiens |
4 | Taken together, these results suggest that (+)-nootkatone may suppress TNF-alpha/IFN-gamma-induced TARC/CCL17 and MDC/CCL22 expression in HaCaT cells by inhibiting of PKCzeta and p38 MAPK signaling pathways that lead to activation of NF-kappaB. | nootkatone | C-C motif chemokine ligand 22 | Homo sapiens |