Title : Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity.

Pub. Date : 2014 Jun

PMID : 24699213






1 Functional Relationships(s)
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1 We found that systemic administration of cyclo(His-Pro) exerts in vivo anti-inflammatory effects in the central nervous system by down-regulating hepatic and cerebral TNFalpha expression thereby counteracting LPS-induced gliosis. Histidine tumor necrosis factor Homo sapiens