Pub. Date : 1989 Apr
PMID : 2469646
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Eosinophil granule major basic protein (MBP) is a 13,800 MW arginine-rich polypeptide that is unique among basic molecules in its ability to stimulate human basophil histamine release. | Histamine | myelin basic protein | Homo sapiens |
| 2 | We examined the Ca2+ requirements and pharmacological regulation of MBP-stimulated histamine release. | Histamine | myelin basic protein | Homo sapiens |
| 3 | Minimal MBP-induced histamine release occurred in the absence of extracellular Ca2+, whereas addition of 0.1 mM Ca2+ resulted in 70% of the maximum histamine release response. | Histamine | myelin basic protein | Homo sapiens |
| 4 | The MBP-induced histamine release was blocked by a calmodulin antagonist and by theophylline and was partially inhibited by an inhibitor of phospholipase A2. | Histamine | myelin basic protein | Homo sapiens |
| 5 | Histamine release stimulated by a 13,900 MW poly-L-arginine exhibited a dissimilar pharmacological profile from that of MBP. | Histamine | myelin basic protein | Homo sapiens |