Title : Xamoterol activates beta 1- but not beta 2-adrenoceptors in mammalian myocardium: comparison of its affinity for beta 1- and beta 2-adrenoceptors coupled to the adenylate cyclase in feline and human ventricle with positive inotropic effects.

Pub. Date : 1989 Jan

PMID : 2468921






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In human ventricular membranes xamoterol stimulated marginally the adenylate cyclase and antagonized the effects of (-)-norepinephrine with a 30-fold greater affinity for beta 1- than for beta 2-adrenoceptors. Norepinephrine potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens