Title : Fibronectin enhances spinal cord astrocyte proliferation by elevating P2Y1 receptor expression.

Pub. Date : 2014 Aug

PMID : 24687862






1 Functional Relationships(s)
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1 In this study, fibronectin stimulated spinal cord astrocytic proliferation from two directions: fibronectin increased astrocytic proliferation via alpha5 beta1 integrin receptor, and fibronectin upregulated the expression of P2Y1 receptor, and adenosine triphosphate (ATP) could enhance the astrocytic proliferation and induce more release of arachidonic acid and prostaglandin E2 via P2Y1. Dinoprostone fibronectin 1 Homo sapiens