Title : Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease.

Pub. Date : 2014 May 6

PMID : 24681980






2 Functional Relationships(s)
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1 In an effort to develop multipotent agents against beta-secretase (BACE-1) and acetylcholinesterase (AChE), able to counteract intracellular ROS formation as well, the structure of the fluorinated benzophenone 3 served as starting point for the synthesis of a small library of 3-fluoro-4-hydroxy- analogues. benzophenone acetylcholinesterase (Cartwright blood group) Homo sapiens
2 In an effort to develop multipotent agents against beta-secretase (BACE-1) and acetylcholinesterase (AChE), able to counteract intracellular ROS formation as well, the structure of the fluorinated benzophenone 3 served as starting point for the synthesis of a small library of 3-fluoro-4-hydroxy- analogues. benzophenone acetylcholinesterase (Cartwright blood group) Homo sapiens