Title : Pharmacological modulation of abnormal involuntary DOI-induced head twitch response in male DBA/2J mice: I. Effects of D2/D3 and D2 dopamine receptor selective compounds.

Pub. Date : 2014 Aug

PMID : 24680675






1 Functional Relationships(s)
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1 For this study we selected the murine 5HT2A/2C receptor agonist-induced head twitch response (HTR) induced by the administration of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), which has been proposed as an animal model of symptoms associated with a variety of behavioral and psychiatric conditions. 4-iodo-2,5-dimethoxyphenylisopropylamine 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus