Title : Rutin potentiates insulin receptor kinase to enhance insulin-dependent glucose transporter 4 translocation.

Pub. Date : 2014 Jun

PMID : 24668568






2 Functional Relationships(s)
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1 SCOPE: We investigated whether rutin, a flavonoid isolated from Toona sinensis Roem, has the ability to enhance insulin-dependent receptor kinase (IRK) activity and glucose transporter 4 (GLUT4) translocation in differentiated myotubes. Rutin solute carrier family 2 (facilitated glucose transporter), member 4 Mus musculus
2 CONCLUSION: This study shows evidence that rutin may serve as a potential agent for glycemic control through enhancement of IRK activity, thereby inducing the insulin signaling pathway causing increased GLUT4 translocation and increased glucose uptake. Rutin solute carrier family 2 (facilitated glucose transporter), member 4 Mus musculus