Pub. Date : 2014 Mar 7
PMID : 24662068
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we report that Rb1 exhibits potent neuroprotective effects against oxidative injury induced by tert-butylhydroperoxide (t-BHP). | tert-Butylhydroperoxide | RB transcriptional corepressor 1 | Rattus norvegicus |
| 2 | Here we report that Rb1 exhibits potent neuroprotective effects against oxidative injury induced by tert-butylhydroperoxide (t-BHP). | tert-Butylhydroperoxide | RB transcriptional corepressor 1 | Rattus norvegicus |
| 3 | Lactate dehydrogenase (LDH) assay demonstrated that incubation with 300 microm t-BHP for 2.5 h led to a significant cell loss of cultured rat embryonic cortex-derived neural progenitor cells (NPCs) and the cell viability was pronouncedly increased by 24 h pretreatment of 10 microm Rb1. | tert-Butylhydroperoxide | RB transcriptional corepressor 1 | Rattus norvegicus |
| 4 | TUNEL staining further confirmed that pretreatment of Rb1 significantly reduced the cell apoptosis in t-BHP-induced oxidative injury. | tert-Butylhydroperoxide | RB transcriptional corepressor 1 | Rattus norvegicus |