Title : Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling.

Pub. Date : 2014

PMID : 24658359






1 Functional Relationships(s)
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1 Verapamil enhanced gene expressions of chondrogenic markers of ACAN encoding aggrecan, COL2A1 encoding collagen type II alpha1, and SOX9, and suppressed Wnt-responsive AXIN2 and MMP3 in human OA chondrocytes. Verapamil aggrecan Homo sapiens