Title : Metabolism of a representative oxygenated polycyclic aromatic hydrocarbon (PAH) phenanthrene-9,10-quinone in human hepatoma (HepG2) cells.

Pub. Date : 2014 May 19

PMID : 24646012






1 Functional Relationships(s)
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1 The identification of 9,10-catechol conjugates supports metabolic detoxification of phenanthrene-9,10-quinone through interception of redox cycling by UGT, COMT, and SULT isozymes and indicates the possible use of phenanthrene-9,10-catechol conjugates as biomarkers of human exposure to oxygenated PAH. 9,10-phenanthrenequinone UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens