Title : Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in the brain.

Pub. Date : 2014 May 2

PMID : 24644281






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 FABP5 both promotes the hydrolysis of AEA into arachidonic acid and thus reduces brain endocannabinoid levels, and directly shuttles arachidonic acid to the nucleus where it delivers it to PPARbeta/delta, enabling its activation. Arachidonic Acid fatty acid binding protein 5, epidermal Mus musculus
2 FABP5 both promotes the hydrolysis of AEA into arachidonic acid and thus reduces brain endocannabinoid levels, and directly shuttles arachidonic acid to the nucleus where it delivers it to PPARbeta/delta, enabling its activation. Arachidonic Acid fatty acid binding protein 5, epidermal Mus musculus