Title : Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors.

Pub. Date : 2014 May 30

PMID : 24632590






1 Functional Relationships(s)
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1 In this respect, rucaparib inhibits nine kinases with micromolar affinity, including PIM1, PIM2, PRKD2, DYRK1A, CDK1, CDK9, HIPK2, CK2, and ALK. rucaparib homeodomain interacting protein kinase 2 Homo sapiens