Title : Inhibitory GEF phosphorylation provides negative feedback in the yeast polarity circuit.

Pub. Date : 2014 Mar 31

PMID : 24631237






1 Functional Relationships(s)
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1 We further show that replacing the GEF with a phosphosite mutant GEF abolishes oscillations and leads to the accumulation of excess GTP-Cdc42 and other polarity factors at the front. Guanosine Triphosphate Rho family GTPase CDC42 Saccharomyces cerevisiae S288C