Title : The absence of core fucose up-regulates GnT-III and Wnt target genes: a possible mechanism for an adaptive response in terms of glycan function.

Pub. Date : 2014 Apr 25

PMID : 24619415






1 Functional Relationships(s)
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1 In this study, we show that, in mouse embryonic fibroblasts (MEFs) from Fut8(-/-) mice, another N-glycan branching structure, bisecting GlcNAc, is specifically up-regulated by enhanced gene expression of the responsible enzyme N-acetylglucosaminyltransferase III (GnT-III). n-glycan mannoside acetylglucosaminyltransferase 3 Mus musculus