Title : The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss.

Pub. Date : 2014 Aug

PMID : 24616121






1 Functional Relationships(s)
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1 In ovariectomized mice cyclicCHAD improved bone mass by both a preventive and a curative treatment protocol, with an effect in line with that of the bisphosphonate alendronate, that was mimicked by the NOS2 inhibitor [L-N6-(1-Iminoethyl)-lysine.2 dihydrochloride]. N(6)-(1-iminoethyl)lysine nitric oxide synthase 2, inducible Mus musculus