Title : Are SR Ca content fluctuations or SR refractoriness the key to atrial cardiac alternans?: insights from a human atrial model.

Pub. Date : 2014 Jun 1

PMID : 24610921






2 Functional Relationships(s)
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1 However, cytosolic calcium alternans observed without concurrent oscillations in the SR Ca content suggests an alternative mechanism related to a dysfunction in the dynamics of the ryanodine receptor (RyR2). Calcium ryanodine receptor 2 Homo sapiens
2 The genesis of calcium alternans was studied stimulating the cell for different periods and values of the RyR2 recovery time from inactivation. Calcium ryanodine receptor 2 Homo sapiens