Title : Transforming growth factor-beta signaling leads to uPA/PAI-1 activation and metastasis: a study on human breast cancer tissues.

Pub. Date : 2014 Jul

PMID : 24610082






1 Functional Relationships(s)
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1 Therefore, protein expression of specific effector molecules comprising the main parts of the TGF-beta signaling pathway were determined in HOPE-fixed human tumor tissues through IHC (Scoring) using tissue microarray (TMA) technique and correlated with respective uPA and PAI-1 levels determined earlier in the same TMAs through optimized IHC and semi-quantitative image analysis. 4,4-dimethylcholesta-8,14-dien-3-ol transforming growth factor beta 1 Homo sapiens