Pub. Date : 2014 Apr
PMID : 24602846
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer. | taxane | heat shock protein family A (Hsp70) member 5 | Homo sapiens |
| 2 | Subgroup analysis revealed that the HR in the GRP78-high group increased significantly in patients who did not receive taxane-containing regimens (HR, 2.21; 95% CI, 1.23-7.36; P=0.038). | taxane | heat shock protein family A (Hsp70) member 5 | Homo sapiens |
| 3 | In contrast, in the patients who received taxane-based chemotherapy, the association between GRP78 positivity and increased risk of recurrence was not statistically significant (HR, 1.16; 95% CI, 0.81-2.98; P=0.111). | taxane | heat shock protein family A (Hsp70) member 5 | Homo sapiens |
| 4 | In the patients with GRP78 expression, those who underwent taxane-containing chemotherapy had longer median TTRs than did those who did not undergo this treatment (P=0.017). | taxane | heat shock protein family A (Hsp70) member 5 | Homo sapiens |