Title : The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats.

Pub. Date : 2014 May

PMID : 24598128






1 Functional Relationships(s)
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1 Because of these unexpected results, we examined CYP2C activity in microsomes and found that treatment of rats with dicoumarol alone and in combination with AAI inhibited CYP2C6/11 in liver. Dicumarol cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus