Title : Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.

Pub. Date : 2014

PMID : 24598074






1 Functional Relationships(s)
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1 The superoxide-generating NADPH oxidase of phagocytes consists of the membrane-associated cytochrome b 558 (a heterodimer of Nox2 and p22(phox)) and 4 cytosolic components: p47(phox), p67(phox), p40(phox), and the small GTPase, Rac, in complex with RhoGDI. Superoxides pleckstrin Homo sapiens