Title : Short-term resveratrol exposure causes in vitro and in vivo growth inhibition and apoptosis of bladder cancer cells.

Pub. Date : 2014

PMID : 24587049






1 Functional Relationships(s)
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1 The results revealed that 2 h 150 microM or 200 microM resveratrol treatment leaded to remarkable S phase arrest and apoptosis at 72 h time-point, accompanied with attenuated phosphorylation, nuclear translocation and transcription of STAT3, down-regulation of STAT3 downstream genes (survivin, cyclinD1, c-Myc and VEGF) and nuclear translocations of Sirt1 and p53. Resveratrol transformation related protein 53, pseudogene Mus musculus