Pub. Date : 2014
PMID : 24586576
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The addition of high phosphate to MSC promoted nuclear translocation of Smad1/5/8 and the activation of canonical Wnt/beta-catenin in addition to an increase in BMP-2 expression, calcium deposition and alkaline phosphatase activity. | Phosphates | SMAD family member 1 | Homo sapiens |
| 2 | Moreover, TGF-beta prevents high phosphate-induced osteogenesis by decreasing the nuclear translocation of Smad 1/5/8 and avoiding the activation of Wnt/beta-catenin pathway. | Phosphates | SMAD family member 1 | Homo sapiens |