Title : Dual role of C/EBPα as an activator and repressor of Gαi2 gene transcription.

Pub. Date : 2013 Dec

PMID : 24580717






2 Functional Relationships(s)
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1 Using HepG2 and K562 cells in culture, we show here that whereas both C/EBPalpha and C/EBPbeta induced transcription from the Galphai2 gene promoter, C/EBPalpha, but not C/EBPbeta, inhibited butyrate-induced Galphai2 expression. Butyrates CCAAT enhancer binding protein alpha Homo sapiens
2 ChIP analysis showed decreased butyrate-induced recruitment of Sp1 to the Galphai2 gene promoter in response to C/EBPalpha treatment. Butyrates CCAAT enhancer binding protein alpha Homo sapiens