Title : miR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer.

Pub. Date : 2015 Jan

PMID : 24576072






2 Functional Relationships(s)
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1 Over-expression of a miR-181a mimic induced an in vitro EMT-like change with a phenotype similar to that seen with TGF-beta treatment alone and was reversed using a miR-181a inhibitor. mir-181a transforming growth factor beta 1 Homo sapiens
2 CONCLUSIONS: MiR-181a had a direct effect in inducing hepatocyte EMT and was able to replace TGF-beta-induced effects in vitro. mir-181a transforming growth factor beta 1 Homo sapiens