Pub. Date : 2014 Apr
PMID : 24569458
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma. | Sorafenib | A-Raf proto-oncogene, serine/threonine kinase | Homo sapiens |
| 2 | The ARAF mutations were shown to transform immortalized human airway epithelial cells in a sorafenib-sensitive manner. | Sorafenib | A-Raf proto-oncogene, serine/threonine kinase | Homo sapiens |
| 3 | These results suggest that mutant ARAF is an oncogenic driver in lung adenocarcinoma and an indicator of sorafenib response. | Sorafenib | A-Raf proto-oncogene, serine/threonine kinase | Homo sapiens |