Title : Oxymatrine triggers apoptosis by regulating Bcl-2 family proteins and activating caspase-3/caspase-9 pathway in human leukemia HL-60 cells.

Pub. Date : 2014 Jun

PMID : 24563336






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In addition, pretreatment with a specific caspase-3 (Z-DEVD-FMK) or caspase-9 (Z-LEHD-FMK) inhibitor significantly neutralized the pro-apoptotic activity of oxymatrine in HL-60 cells, demonstrating the important role of caspase-3 and caspase-9 in this process. benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone caspase 3 Homo sapiens