Pub. Date : 2014 May 1
PMID : 24561178
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acrolein relaxes mouse isolated tracheal smooth muscle via a TRPA1-dependent mechanism. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 2 | TRPA1 likely plays an intermediary role in eliciting a range of effects induced by acrolein including cough and neurogenic inflammation. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 3 | Currently, it is not known whether acrolein-induced activation of TRPA1 produces other airway effects including relaxation of mouse airway smooth muscle. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 4 | Pharmacologic studies indicate that acrolein-induced relaxation likely involves interplay between TRPA1-expressing airway sensory C-fibres, NK1 receptor-expressing epithelial cells, and EP2-receptor expressing airway smooth muscle cells. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |