Title : Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor.

Pub. Date : 2014 Mar 21

PMID : 24556146






2 Functional Relationships(s)
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1 The designed glycomimetics were evaluated by in vitro assay of the isolated DC-SIGN extracellular domain for their ability to compete with HIV-1 gp120 for binding to the DC-SIGN carbohydrate recognition domain. Carbohydrates CD209 molecule Homo sapiens
2 The designed glycomimetics were evaluated by in vitro assay of the isolated DC-SIGN extracellular domain for their ability to compete with HIV-1 gp120 for binding to the DC-SIGN carbohydrate recognition domain. Carbohydrates CD209 molecule Homo sapiens