Pub. Date : 2014 Mar 4
PMID : 24550461
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Upon activation by tryptophan, the outer circumference of the TRAP ring binds specifically to a series of tandem sequences present in the 5" UTR of RNA transcripts encoding several tryptophan metabolism genes, leading to their silencing. | Tryptophan | TRAP | Homo sapiens |
| 2 | Upon activation by tryptophan, the outer circumference of the TRAP ring binds specifically to a series of tandem sequences present in the 5" UTR of RNA transcripts encoding several tryptophan metabolism genes, leading to their silencing. | Tryptophan | TRAP | Homo sapiens |
| 3 | AT, whose expression is up-regulated upon tryptophan depletion to concentrations not exceeding a ratio of one AT trimer per TRAP 11-mer, restores tryptophan production by binding activated TRAP and preventing RNA binding. | Tryptophan | TRAP | Homo sapiens |
| 4 | AT, whose expression is up-regulated upon tryptophan depletion to concentrations not exceeding a ratio of one AT trimer per TRAP 11-mer, restores tryptophan production by binding activated TRAP and preventing RNA binding. | Tryptophan | TRAP | Homo sapiens |
| 5 | AT, whose expression is up-regulated upon tryptophan depletion to concentrations not exceeding a ratio of one AT trimer per TRAP 11-mer, restores tryptophan production by binding activated TRAP and preventing RNA binding. | Tryptophan | TRAP | Homo sapiens |
| 6 | How the smaller AT inhibitor prevents RNA binding at such low stoichiometries has remained a puzzle, in part because of the large RNA-binding surface on the tryptophan-activated TRAP ring and its high affinity for RNA. | Tryptophan | TRAP | Homo sapiens |