Pub. Date : 2014 Apr
PMID : 24535284
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PURPOSE OF REVIEW: We summarize recent mechanistic and physiological studies related to the role of perilipin 5 (Plin5) in regulating lipid droplet accumulation and protection to fatty acids in tissues with high lipid oxidative metabolism. | Fatty Acids | perilipin 5 | Mus musculus |
| 2 | PURPOSE OF REVIEW: We summarize recent mechanistic and physiological studies related to the role of perilipin 5 (Plin5) in regulating lipid droplet accumulation and protection to fatty acids in tissues with high lipid oxidative metabolism. | Fatty Acids | perilipin 5 | Mus musculus |
| 3 | These data suggest a cytoprotective role for Plin5 to promote lipid storage but to limit fatty acid toxicity, parameters critical for tissues with high lipid oxidative metabolism. | Fatty Acids | perilipin 5 | Mus musculus |
| 4 | SUMMARY: In-vivo and in-vitro data suggest that Plin5 is part of a cell-adaptive response to high lipid oxidative metabolism to protect lipid droplet storage against neutral lipases and, so, limit fatty acid accumulation. | Fatty Acids | perilipin 5 | Mus musculus |