Title : Role of extracellular calcium in the effects of substance P and neurokinin A on guinea pig trachea and human bronchus.

Pub. Date : 1988

PMID : 2453427






2 Functional Relationships(s)
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1 Calcium antagonists such as verapamil or nicardipine, when applied at concentrations of 10(-8)-10(-6) M, inhibited the contractions produced by potassium chloride and tetraethylammonium, whereas higher concentrations (10(-5)-10(-4) M) of both inhibitors were needed to reduce the effects of substance P, neurokinin A, acetylcholine, and histamine. Tetraethylammonium tachykinin precursor 1 Homo sapiens
2 Calcium antagonists such as verapamil or nicardipine, when applied at concentrations of 10(-8)-10(-6) M, inhibited the contractions produced by potassium chloride and tetraethylammonium, whereas higher concentrations (10(-5)-10(-4) M) of both inhibitors were needed to reduce the effects of substance P, neurokinin A, acetylcholine, and histamine. Tetraethylammonium tachykinin precursor 1 Homo sapiens