Pub. Date : 2014
PMID : 24532971
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, DCA significantly enhanced interferon (IFN)-gamma but not interleukin (IL)-17 production levels in unstimulated and stimulated mouse spleen cells. | Dichloroacetic Acid | interferon gamma | Mus musculus |
| 2 | To investigate the mechanism of DCA on IFN-gamma production, DCA cytokine modulatory effect was tested on unstimulated macrophages, T-cells, and natural killer cells. | Dichloroacetic Acid | interferon gamma | Mus musculus |
| 3 | Moreover, the DCA-enhancing effect on IFN-gamma production was reversed by anti-IL-12 antibody. | Dichloroacetic Acid | interferon gamma | Mus musculus |
| 4 | DCA restored PMA-lowered IFN-gamma and IL-12 levels and normalized PMA-increased transforming growth factor-beta level, but it inhibited IL-10 levels even further (P<0.05). | Dichloroacetic Acid | interferon gamma | Mus musculus |