Title : Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions.

Pub. Date : 2014 Jun

PMID : 24528233






1 Functional Relationships(s)
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1 Studies conducted with brain microvascular endothelial cells exposed to OGD +- R in the presence of Y-27632 revealed restoration of intercellular junctions and suppression of prooxidant NADPH oxidase activity as important factors in ROCK inhibition-mediated BBB protection. Y 27632 Rho-associated coiled-coil containing protein kinase 2 Mus musculus