Title : MicroRNA-492 reverses high glucose-induced insulin resistance in HUVEC cells through targeting resistin.

Pub. Date : 2014 Jun

PMID : 24526524






3 Functional Relationships(s)
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1 MicroRNA-492 reverses high glucose-induced insulin resistance in HUVEC cells through targeting resistin. Glucose resistin Homo sapiens
2 Our results showed that high glucose stress induced a significant decrease in miR-492 expression, with a remarkable upregulation of resistin expression. Glucose resistin Homo sapiens
3 Together, our findings indicate that miR-492 contributes to insulin resistance and endothelial dysfunction induced by high glucose, via directly downregulating resistin expression, and involving STAT3 phosphorylation, SOCS, and P-selectin activation. Glucose resistin Homo sapiens