Title : Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury.

Pub. Date : 2014 Jun

PMID : 24511121

1 Functional Relationships(s)
Compound Name
Protein Name
1 Thrombospondin-1 also stimulated phosphorylation of p47(phox) (an organizer subunit for nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 1/2) and increased production of superoxide, both of which were abrogated by knockdown or antibody blockade of SIRP-alpha. Superoxides pleckstrin Homo sapiens