Pub. Date : 2014 Mar-Apr
PMID : 24492289
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the first approach, we generated a bispecific anti-HER2/HER3 antibody that, in the presence of lapatinib, is designed to sequester HER3 into inactive HER2-HER3 dimers that restrain HER3 interactions with other possible dimerization partners. | Lapatinib | erb-b2 receptor tyrosine kinase 3 | Homo sapiens |
| 2 | In the first approach, we generated a bispecific anti-HER2/HER3 antibody that, in the presence of lapatinib, is designed to sequester HER3 into inactive HER2-HER3 dimers that restrain HER3 interactions with other possible dimerization partners. | Lapatinib | erb-b2 receptor tyrosine kinase 3 | Homo sapiens |
| 3 | In the first approach, we generated a bispecific anti-HER2/HER3 antibody that, in the presence of lapatinib, is designed to sequester HER3 into inactive HER2-HER3 dimers that restrain HER3 interactions with other possible dimerization partners. | Lapatinib | erb-b2 receptor tyrosine kinase 3 | Homo sapiens |
| 4 | In the first approach, we generated a bispecific anti-HER2/HER3 antibody that, in the presence of lapatinib, is designed to sequester HER3 into inactive HER2-HER3 dimers that restrain HER3 interactions with other possible dimerization partners. | Lapatinib | erb-b2 receptor tyrosine kinase 3 | Homo sapiens |