Title : Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation.

Pub. Date : 2014 Mar 1

PMID : 24489094






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The prolyl-tRNA synthetase inhibitor halofuginone blocks IL-23-induced Stat3 phosphorylation and IL-23-dependent proinflammatory cytokine expression in endogenous CCR6(+) Th17 cells via activation of the amino acid starvation response (AAR) pathway. halofuginone interleukin 23, alpha subunit p19 Mus musculus
2 The prolyl-tRNA synthetase inhibitor halofuginone blocks IL-23-induced Stat3 phosphorylation and IL-23-dependent proinflammatory cytokine expression in endogenous CCR6(+) Th17 cells via activation of the amino acid starvation response (AAR) pathway. halofuginone interleukin 23, alpha subunit p19 Mus musculus