Title : Pro-apoptotic Sorafenib signaling in murine hepatocytes depends on malignancy and is associated with PUMA expression in vitro and in vivo.

Pub. Date : 2014 Jan 30

PMID : 24481444






1 Functional Relationships(s)
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1 In vitro, we demonstrate that cell cycle activity and expression of anti-apoptotic Bcl-2 like proteins are similarly downregulated by Sorafenib in Hepa1-6 hepatoma cells and in syngeneic primary hepatocytes. Sorafenib B cell leukemia/lymphoma 2 Mus musculus